{
  "id": 5318,
  "name": "elapegademase",
  "cas_reg_no": "1709806-75-6",
  "smiles": null,
  "inchikey": null,
  "inchi": null,
  "formula": "",
  "molweight": null,
  "xrefs": [
    {
      "xref_type": "VANDF",
      "xref": "4038007"
    },
    {
      "xref_type": "VANDF",
      "xref": "4038008"
    },
    {
      "xref_type": "UMLSCUI",
      "xref": "C4731737"
    },
    {
      "xref_type": "ChEMBL_ID",
      "xref": "CHEMBL3990026"
    },
    {
      "xref_type": "DRUGBANK_ID",
      "xref": "DB14712"
    },
    {
      "xref_type": "KEGG_DRUG",
      "xref": "D11017"
    },
    {
      "xref_type": "MESH_SUPPLEMENTAL_RECORD_UI",
      "xref": "C000645732"
    },
    {
      "xref_type": "PUBCHEM_CID",
      "xref": "121488177"
    },
    {
      "xref_type": "INN_ID",
      "xref": "10378"
    },
    {
      "xref_type": "UNII",
      "xref": "9R3D3Y0UHS"
    },
    {
      "xref_type": "RXNORM",
      "xref": "2059218"
    },
    {
      "xref_type": "MMSL",
      "xref": "294366"
    },
    {
      "xref_type": "MMSL",
      "xref": "35316"
    },
    {
      "xref_type": "MMSL",
      "xref": "d09011"
    },
    {
      "xref_type": "NDDF",
      "xref": "017797"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "782147005"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "782152000"
    }
  ],
  "synonyms": [
    "EZN-2279",
    "elapegademase",
    "elapegademase-lvlr",
    "revcovi"
  ],
  "atcs": [
    {
      "atc_code": "G04CX01",
      "atc_l1_code": "G",
      "atc_l1_name": "GENITO URINARY SYSTEM AND SEX HORMONES",
      "atc_l2_code": "G04",
      "atc_l2_name": "UROLOGICALS",
      "atc_l3_code": "G04C",
      "atc_l3_name": "DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY",
      "atc_l4_code": "G04CX",
      "atc_l4_name": "Other drugs used in benign prostatic hypertrophy",
      "atc_substance": "Prunus africanae cortex"
    }
  ],
  "products": [
    {
      "product_id": 2423685,
      "ndc_product_code": "57665-002",
      "product_form": "INJECTION",
      "product_generic_name": "elapegademase-lvlr",
      "product_name": "Revcovi",
      "product_route": "INTRAMUSCULAR",
      "product_marketing_status": "BLA",
      "product_active_ingredient_count": 1
    },
    {
      "product_id": 2434263,
      "ndc_product_code": "10122-502",
      "product_form": "INJECTION",
      "product_generic_name": "elapegademase-lvlr",
      "product_name": "Revcovi",
      "product_route": "INTRAMUSCULAR",
      "product_marketing_status": "BLA",
      "product_active_ingredient_count": 1
    }
  ],
  "targets": [
    {
      "target_id": 4245,
      "target_name": "adenosine",
      "gene": null,
      "action_type": "OTHER",
      "act_source": "UNKNOWN",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": 1,
      "moa_source": "DRUG LABEL",
      "moa_source_url": "https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/761092s000lbl.pdf",
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": 2018
    }
  ],
  "indications": [
    {
      "omop_concept_id": 40249348,
      "omop_concept_name": "SCID due to absent adenosine deaminase",
      "umls_cui": "C0272230",
      "umls_semantic_type": "T047",
      "snomed_conceptid": 36980009,
      "snomed_full_name": "SCID due to absent adenosine deaminase"
    }
  ]
}