{
  "id": 4305,
  "name": "avanafil",
  "cas_reg_no": "330784-47-9",
  "smiles": "COC1=C(Cl)C=C(CNC2=NC(=NC=C2C(=O)NCC2=NC=CC=N2)N2CCC[C@H]2CO)C=C1",
  "inchikey": "WEAJZXNPAWBCOA-INIZCTEOSA-N",
  "inchi": "InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1",
  "formula": "C23H26ClN7O3",
  "molweight": 483.96,
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      "xref_type": "UNII",
      "xref": "DR5S136IVO"
    },
    {
      "xref_type": "KEGG_DRUG",
      "xref": "D03217"
    },
    {
      "xref_type": "VANDF",
      "xref": "4032978"
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      "xref_type": "UMLSCUI",
      "xref": "C2698280"
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    {
      "xref_type": "CHEBI",
      "xref": "CHEBI:66876"
    },
    {
      "xref_type": "PDB_CHEM_ID",
      "xref": "E6L"
    },
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      "xref_type": "ChEMBL_ID",
      "xref": "CHEMBL1963681"
    },
    {
      "xref_type": "DRUGBANK_ID",
      "xref": "DB06237"
    },
    {
      "xref_type": "PUBCHEM_CID",
      "xref": "9869929"
    },
    {
      "xref_type": "INN_ID",
      "xref": "8572"
    },
    {
      "xref_type": "MESH_SUPPLEMENTAL_RECORD_UI",
      "xref": "C553414"
    },
    {
      "xref_type": "IUPHAR_LIGAND_ID",
      "xref": "7448"
    },
    {
      "xref_type": "RXNORM",
      "xref": "1291301"
    },
    {
      "xref_type": "MMSL",
      "xref": "189434"
    },
    {
      "xref_type": "MMSL",
      "xref": "28514"
    },
    {
      "xref_type": "MMSL",
      "xref": "d07863"
    },
    {
      "xref_type": "NDDF",
      "xref": "015259"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "703956007"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "703957003"
    }
  ],
  "synonyms": [
    "TA 1790",
    "avanafil",
    "spedra",
    "stendra"
  ],
  "atcs": [
    {
      "atc_code": "C10AD02",
      "atc_l1_code": "C",
      "atc_l1_name": "CARDIOVASCULAR SYSTEM",
      "atc_l2_code": "C10",
      "atc_l2_name": "LIPID MODIFYING AGENTS",
      "atc_l3_code": "C10A",
      "atc_l3_name": "LIPID MODIFYING AGENTS, PLAIN",
      "atc_l4_code": "C10AD",
      "atc_l4_name": "Nicotinic acid and derivatives",
      "atc_substance": "nicotinic acid"
    }
  ],
  "products": [
    {
      "product_id": 2414113,
      "ndc_product_code": "72384-751",
      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
      "product_marketing_status": "NDA",
      "product_active_ingredient_count": 1
    },
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      "product_id": 2414114,
      "ndc_product_code": "72384-752",
      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
      "product_marketing_status": "NDA",
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    },
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      "product_id": 2414115,
      "ndc_product_code": "72384-753",
      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
      "product_marketing_status": "NDA",
      "product_active_ingredient_count": 1
    },
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      "product_id": 2437995,
      "ndc_product_code": "76299-320",
      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
      "product_marketing_status": "NDA",
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    },
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      "ndc_product_code": "76299-321",
      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
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    {
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      "product_form": "TABLET",
      "product_generic_name": "avanafil",
      "product_name": "Stendra",
      "product_route": "ORAL",
      "product_marketing_status": "NDA",
      "product_active_ingredient_count": 1
    }
  ],
  "targets": [
    {
      "target_id": 411,
      "target_name": "cGMP-specific 3',5'-cyclic phosphodiesterase",
      "gene": "PDE5A",
      "action_type": "INHIBITOR",
      "act_source": "WOMBAT-PK",
      "act_type": "IC50",
      "act_comment": null,
      "relation": "=",
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      "moa_source": "CHEMBL",
      "moa_source_url": "https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL1963681",
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      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
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      "target_id": 770,
      "target_name": "Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'",
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      "ref_doi": null,
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    {
      "omop_concept_id": 21002383,
      "omop_concept_name": "Impotence",
      "umls_cui": "C0242350",
      "umls_semantic_type": "T047",
      "snomed_conceptid": 397803000,
      "snomed_full_name": "Impotence"
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}