{
  "id": 1950,
  "name": "nitrofurazone",
  "cas_reg_no": "59-87-0",
  "smiles": "NC(=O)N\\N=C\\C1=CC=C(O1)[N+]([O-])=O",
  "inchikey": "IAIWVQXQOWNYOU-FPYGCLRLSA-N",
  "inchi": "InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+",
  "formula": "C6H6N4O4",
  "molweight": 198.138,
  "xrefs": [
    {
      "xref_type": "VUID",
      "xref": "4018879"
    },
    {
      "xref_type": "NUI",
      "xref": "N0000147174"
    },
    {
      "xref_type": "KEGG_DRUG",
      "xref": "D00862"
    },
    {
      "xref_type": "VANDF",
      "xref": "4018879"
    },
    {
      "xref_type": "UMLSCUI",
      "xref": "C0740138"
    },
    {
      "xref_type": "CHEBI",
      "xref": "CHEBI:44368"
    },
    {
      "xref_type": "PDB_CHEM_ID",
      "xref": "NFZ"
    },
    {
      "xref_type": "ChEMBL_ID",
      "xref": "CHEMBL869"
    },
    {
      "xref_type": "DRUGBANK_ID",
      "xref": "DB00336"
    },
    {
      "xref_type": "PUBCHEM_CID",
      "xref": "5447130"
    },
    {
      "xref_type": "MESH_DESCRIPTOR_UI",
      "xref": "D009583"
    },
    {
      "xref_type": "INN_ID",
      "xref": "4160"
    },
    {
      "xref_type": "UNII",
      "xref": "X8XI70B5Z6"
    },
    {
      "xref_type": "RXNORM",
      "xref": "227727"
    },
    {
      "xref_type": "MMSL",
      "xref": "2323"
    },
    {
      "xref_type": "MMSL",
      "xref": "402"
    },
    {
      "xref_type": "MMSL",
      "xref": "5182"
    },
    {
      "xref_type": "NDDF",
      "xref": "002857"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "332799007"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "87097009"
    }
  ],
  "synonyms": [
    "aldomycin",
    "babrocid",
    "furacilin",
    "furacin",
    "furacine",
    "furacycline",
    "furaldon",
    "furaziline",
    "nifuzon",
    "nitrofural",
    "nitrofuraldehyde semicarbazone",
    "nitrofuran",
    "nitrofurazone",
    "nitrozone"
  ],
  "atcs": [
    {
      "atc_code": "A12CC03",
      "atc_l1_code": "A",
      "atc_l1_name": "ALIMENTARY TRACT AND METABOLISM",
      "atc_l2_code": "A12",
      "atc_l2_name": "MINERAL SUPPLEMENTS",
      "atc_l3_code": "A12C",
      "atc_l3_name": "OTHER MINERAL SUPPLEMENTS",
      "atc_l4_code": "A12CC",
      "atc_l4_name": "Magnesium",
      "atc_substance": "magnesium gluconate"
    },
    {
      "atc_code": "C04AE04",
      "atc_l1_code": "C",
      "atc_l1_name": "CARDIOVASCULAR SYSTEM",
      "atc_l2_code": "C04",
      "atc_l2_name": "PERIPHERAL VASODILATORS",
      "atc_l3_code": "C04A",
      "atc_l3_name": "PERIPHERAL VASODILATORS",
      "atc_l4_code": "C04AE",
      "atc_l4_name": "Ergot alkaloids",
      "atc_substance": "dihydroergocristine"
    },
    {
      "atc_code": "C05AD05",
      "atc_l1_code": "C",
      "atc_l1_name": "CARDIOVASCULAR SYSTEM",
      "atc_l2_code": "C05",
      "atc_l2_name": "VASOPROTECTIVES",
      "atc_l3_code": "C05A",
      "atc_l3_name": "AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE",
      "atc_l4_code": "C05AD",
      "atc_l4_name": "Local anesthetics",
      "atc_substance": "procaine"
    },
    {
      "atc_code": "L01XC05",
      "atc_l1_code": "L",
      "atc_l1_name": "ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS",
      "atc_l2_code": "L01",
      "atc_l2_name": "ANTINEOPLASTIC AGENTS",
      "atc_l3_code": "L01X",
      "atc_l3_name": "OTHER ANTINEOPLASTIC AGENTS",
      "atc_l4_code": "L01XC",
      "atc_l4_name": "Monoclonal antibodies",
      "atc_substance": "gemtuzumab ozogamicin"
    },
    {
      "atc_code": "M03BA01",
      "atc_l1_code": "M",
      "atc_l1_name": "MUSCULO-SKELETAL SYSTEM",
      "atc_l2_code": "M03",
      "atc_l2_name": "MUSCLE RELAXANTS",
      "atc_l3_code": "M03B",
      "atc_l3_name": "MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS",
      "atc_l4_code": "M03BA",
      "atc_l4_name": "Carbamic acid esters",
      "atc_substance": "phenprobamate"
    },
    {
      "atc_code": "N01BB54",
      "atc_l1_code": "N",
      "atc_l1_name": "NERVOUS SYSTEM",
      "atc_l2_code": "N01",
      "atc_l2_name": "ANESTHETICS",
      "atc_l3_code": "N01B",
      "atc_l3_name": "ANESTHETICS, LOCAL",
      "atc_l4_code": "N01BB",
      "atc_l4_name": "Amides",
      "atc_substance": "prilocaine, combinations"
    }
  ],
  "targets": [
    {
      "target_id": 921,
      "target_name": "Glucose-6-phosphate 1-dehydrogenase",
      "gene": "G6PD",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
    {
      "target_id": 3539,
      "target_name": "Snake venom metalloproteinase Bap1",
      "gene": null,
      "action_type": null,
      "act_source": "CHEMBL",
      "act_type": "IC50",
      "act_comment": "Inhibition of snake venom BaP1 using Abz-Ala-Gly-Leu-Ala-Nba as substrate incubated for 30 mins prior to substrate addition by fluorescence spectrophotometry",
      "relation": "=",
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    }
  ],
  "indications": [
    {
      "omop_concept_id": 21002349,
      "omop_concept_name": "Staphylococcus Saprophyticus Urinary Tract Infection",
      "umls_cui": null,
      "umls_semantic_type": null,
      "snomed_conceptid": NaN,
      "snomed_full_name": null
    },
    {
      "omop_concept_id": 21002327,
      "omop_concept_name": "Escherichia coli urinary tract infection",
      "umls_cui": "C0577708",
      "umls_semantic_type": "T047",
      "snomed_conceptid": 301011002.0,
      "snomed_full_name": "Escherichia coli urinary tract infection"
    },
    {
      "omop_concept_id": 21002332,
      "omop_concept_name": "Staphylococcus Aureus Urinary Tract Infection",
      "umls_cui": null,
      "umls_semantic_type": null,
      "snomed_conceptid": NaN,
      "snomed_full_name": null
    },
    {
      "omop_concept_id": 21002301,
      "omop_concept_name": "Klebsiella cystitis",
      "umls_cui": "C0520775",
      "umls_semantic_type": "T047",
      "snomed_conceptid": 60867007.0,
      "snomed_full_name": "Klebsiella cystitis"
    },
    {
      "omop_concept_id": 21002325,
      "omop_concept_name": "Enterococcus Urinary Tract Infection",
      "umls_cui": null,
      "umls_semantic_type": null,
      "snomed_conceptid": NaN,
      "snomed_full_name": null
    },
    {
      "omop_concept_id": 21002299,
      "omop_concept_name": "Enterobacter Cystitis",
      "umls_cui": null,
      "umls_semantic_type": null,
      "snomed_conceptid": NaN,
      "snomed_full_name": null
    }
  ]
}