{
  "id": 1007,
  "name": "encainide",
  "cas_reg_no": "66778-36-7",
  "smiles": "COC1=CC=C(C=C1)C(=O)NC1=CC=CC=C1CCC1CCCCN1C",
  "inchikey": "PJWPNDMDCLXCOM-UHFFFAOYSA-N",
  "inchi": "InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25)",
  "formula": "C22H28N2O2",
  "molweight": 352.478,
  "xrefs": [
    {
      "xref_type": "VUID",
      "xref": "4019745"
    },
    {
      "xref_type": "NUI",
      "xref": "N0000147836"
    },
    {
      "xref_type": "KEGG_DRUG",
      "xref": "D07894"
    },
    {
      "xref_type": "SECONDARY_CAS_RN",
      "xref": "66794-74-9"
    },
    {
      "xref_type": "VANDF",
      "xref": "4019356"
    },
    {
      "xref_type": "VANDF",
      "xref": "4019745"
    },
    {
      "xref_type": "UMLSCUI",
      "xref": "C0085251"
    },
    {
      "xref_type": "CHEBI",
      "xref": "CHEBI:4788"
    },
    {
      "xref_type": "ChEMBL_ID",
      "xref": "CHEMBL315838"
    },
    {
      "xref_type": "ChEMBL_ID",
      "xref": "CHEMBL2106155"
    },
    {
      "xref_type": "DRUGBANK_ID",
      "xref": "DB01228"
    },
    {
      "xref_type": "MESH_DESCRIPTOR_UI",
      "xref": "D016700"
    },
    {
      "xref_type": "PUBCHEM_CID",
      "xref": "48041"
    },
    {
      "xref_type": "INN_ID",
      "xref": "4472"
    },
    {
      "xref_type": "UNII",
      "xref": "SY3J0147NB"
    },
    {
      "xref_type": "RXNORM",
      "xref": "281189"
    },
    {
      "xref_type": "NDDF",
      "xref": "000631"
    },
    {
      "xref_type": "NDDF",
      "xref": "004486"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "372749000"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "46479001"
    },
    {
      "xref_type": "SNOMEDCT_US",
      "xref": "81017004"
    }
  ],
  "synonyms": [
    "MJ 9067",
    "MJ-9067",
    "encainide",
    "encainide hydrochloride"
  ],
  "atcs": [
    {
      "atc_code": "B01AA01",
      "atc_l1_code": "B",
      "atc_l1_name": "BLOOD AND BLOOD FORMING ORGANS",
      "atc_l2_code": "B01",
      "atc_l2_name": "ANTITHROMBOTIC AGENTS",
      "atc_l3_code": "B01A",
      "atc_l3_name": "ANTITHROMBOTIC AGENTS",
      "atc_l4_code": "B01AA",
      "atc_l4_name": "Vitamin K antagonists",
      "atc_substance": "dicoumarol"
    }
  ],
  "targets": [
    {
      "target_id": 61,
      "target_name": "Sodium channel protein type 5 subunit alpha",
      "gene": "SCN5A",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
    {
      "target_id": 62,
      "target_name": "Sodium channel subunit beta-1",
      "gene": "SCN1B",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
    {
      "target_id": 63,
      "target_name": "Sodium channel subunit beta-2",
      "gene": "SCN2B",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
    {
      "target_id": 64,
      "target_name": "Sodium channel subunit beta-3",
      "gene": "SCN3B",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    },
    {
      "target_id": 65,
      "target_name": "Sodium channel subunit beta-4",
      "gene": "SCN4B",
      "action_type": null,
      "act_source": "WOMBAT-PK",
      "act_type": null,
      "act_comment": null,
      "relation": null,
      "moa": null,
      "moa_source": null,
      "moa_source_url": null,
      "ref_pmid": null,
      "ref_doi": null,
      "ref_title": null,
      "ref_year": null
    }
  ],
  "indications": [
    {
      "omop_concept_id": 21001560,
      "omop_concept_name": "Ventricular premature beats",
      "umls_cui": "C0151636",
      "umls_semantic_type": "T046",
      "snomed_conceptid": 17338001,
      "snomed_full_name": "Ventricular premature beats"
    }
  ]
}